Relationship of severity of COVID-19 disease with lung-CT-scan imaging

Objectives: Lung-CT-scan imaging is known as important diagnostic technique for evaluation of the effectiveness and infectious involvement of the lungs. In this study, we evaluated and analyzed lung CT images in patients with Coronavirus Disease 2019 (COVID-19) and its relationship with some important clinical and laboratory factors as well as the patient's condition in the worst disease conditions. Methods: In this retrospective descriptive-analytical study, 375 patients with complete information have been considered. Among these patients, CT scans of patients' lungs was carefully reevaluated. Other radiologist reviewed the images and recorded the final score of the patients' lung involvement. Results: Data showed that lung and cardiac involvement have high prevalence among studies patients. Among demographic variables, there was significant relationship between age and recovery. Evaluating the relationship of recovery with CT variables showed that CT score, bilateral lung involvement, and Crazy paving had significant effect on recovery rate. Conclusion: According to this study, evaluation of CT variables can be used as potent factors for evaluation of disease status and design of suitable treatment strategy.

The most common symptoms of COVID-19 patients in Yazd

The aim of this study was to investigate the most common symptoms of COVID-19 patients in Yazd. This study was done during 2020-2021. All patients with positive PCR test were entered to this study. Finally, data was analyzed by SPSS software. The most common symptoms of COVID-19 patients were shortness of breath, fever and cough. There was a significant relationship between diabetes, lethargy, myalgia, chills, fever and loss of taste. Several symptoms including weakness, lethargy, dry cough, decreased appetite, were significantly more in the autumn season. According to the findings, the symptoms could have different prevalence in patients with underlying disease.Copyright © 2021 Health Biotechnology And Biopharma. All Rights Reserved.

Infection with Covid Variants of Concern in a Lung Transplant Population

The COVID pandemic has evolved as the SARS-2 Coronavirus (CoV-2) mutated into unique variants of concern (VOC). The clinical approach to COVID has evolved as new therapeutics have become available. Previous reports demonstrate differences in patient outcomes based on VOC, however outcomes in a lung transplant population have not been described. Our lung transplant program follows over 300 transplant recipients. Relevant information including date of first positive test, hospital admission, monoclonal antibody (mAb) or oral anti-viral treatment, CoV-2 vaccination history, tixagevimab/cilgavimab (T/C) and COVID attributed mortality have been tracked for quality improvement purposes. Outcomes were stratified by predominant US VOC at time of positive testing: wild strain 02/2020-02/2021, alpha strain 02/2021-05/2021, delta strain 06/2021-12/2021, omicron strain 01/2022- 09/25/2022. From 03/20/2020 through 09/25/2022, 142 recipients were diagnosed with COVID 152 times, including 9 recipients infected twice and 1 recipient infected 3 times. Most infected recipients tested positive with CoV-2 during the omicron wave. All recurrent infections occurred during the omicron wave. 8 deaths (5.6%) were attributed to COVID: 6 due to COVID respiratory failure, 1 stroke and 1 new restrictive-chronic lung allograft dysfunction. Therapies directed against CoV-2 were more likely administered in delta and omicron waves. Recipients were more likely to require hospital admission in wild type and alpha waves of CoV-2. Most deaths occurred in the wild type and delta waves. Deceased recipients, and those requiring hospital admission received less vaccinations and were less likely to have received T/C. (Table) This analysis shows changing trends in management and outcomes over the COVID pandemic. Future research should focus on transplant specific outcomes, including post-infection changes in allograft function and risk of developing chronic lung allograft dysfunction based on likely infecting VOC. [ABSTRACT FROM AUTHOR] Copyright of Journal of Heart & Lung Transplantation is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Evaluation of ESR, CRP, LDH, CPK, D-Dimer, BS and FBS levels in hospitalized COVID-19 patients with mucormycosis

Mucormycosis in COVID-19 patients of severe type has been reported. This study was intended to evaluate ESR, CRP, LDH, CPK, D-Dimer, BS and FBS levels in COVID-19 patients with mucormycosis. Information was recorded including gender, age, hospitalization and recovery. The laboratory parameters contained ESR, CRP, LDH, CPK, D-Dimer, BS and FBS levels. There was a significant relationship between LDH and CPK level with hospitalization, and also, between CRP and gender. Finally, there was a significant difference between the age groups in terms of ESR. Our study showed that LDH and CPK, CRP and ESR should be considered as laboratory tests in the hospitalized COVID-19 patients with mucormycosis. © 2022, Health Biotechnology and Biopharma.

Relationship between blood albumin level and clinical condition of patients with Covid-19 admitted to Shahid Sadoughi hospital in Yazd

COVID-19 infection is still widespread around the world. It has been demonstrated that albumin is a biomarker in COVID-19 diagnosis. The aim of this study was to investigate the relationship between blood albumin and clinical status of COVID-19 patients. In our study, patients older than 18 years admitted to a hospital in Yazd with a positive PCR test participated. Related data was analyzed by SPSS software. 34.2 % of the men with lower than normal albumin levels needed to be admitted to the ICU. Also, 32.8 % of the women with lower than normal albumin levels needed to be admitted to the ICU. The results of the present study showed that the patients with lower serum albumin needed to be admitted to the ICU more than other patients. © 2022, Health Biotechnology and Biopharma. All rights reserved

The most common symptoms of COVID-19 patients in Yazd

The aim of this study was to investigate the most common symptoms of COVID-19 patients in Yazd. This study was done during 2020-2021. All patients with positive PCR test were entered to this study. Finally, data was analyzed by SPSS software. The most common symptoms of COVID-19 patients were shortness of breath, fever and cough. There was a significant relationship between diabetes, lethargy, myalgia, chills, fever and loss of taste. Several symptoms including weakness, lethargy, dry cough, decreased appetite, were significantly more in the autumn season. According to the findings, the symptoms could have different prevalence in patients with underlying disease. © 2021 Health Biotechnology And Biopharma. All Rights Reserved.